Lesions in AIDS patients

Figure 2 presents MR spectra obtained for a brain lesion and the contralateral region of an AIDS patient. In Figure 3, published spectra (1) of common brain lesions (toxoplasmosis, lymphoma and progressive multifocal leucoencephalopathy) in AIDS patients are presented in addition to the spectrum of the healthy contralateral region. It is obvious, comparing Figures 2 and 3, that the diagnosis of the patient studied is toxoplasmosis.



Fig. 2. Brain spectra of an AIDS patient recorded on the lesion (left) and in the contralateral area (right). The lesion spectrum is compatible with toxoplasmosis (Fig. 3).




Fig. 3. Spectra of common brain lesions observed in AIDS patients (toxoplasmosis, lymphoma and progressive multifocal leucoencephalopathy) as well as the spectrum of the healthy contralateral region (1).

Reference

Chang, L. In vivo magnetic resonance spectroscopy in HIV and HIV-related brain diseases. Rev. Neurosci. 6, 365-378, 1995.