between 20 and 80 years are recruited at the CHUM ALS
Clinic. No patient was under riluzole treatment.
MRS data were acquired at 1.5 T in the precentral gyrus (8 cc) and in
the brainstem (3 cc) using the PRESS sequence with TE = 30 ms or
135 ms. Each patient is examined three times: before minocycline
treatment, 3 weeks and 6 weeks after initiating the treatment. The
NAA/Cr, Cho/Cr, mI/Cr and Glx/Cr ratios are calculated.